Lymphoedema is swelling that is caused by a compromised lymphatic system. Along with the network of arteries and veins in our bodies, there is a network of lymphatic vessels shifting lymph fluid (white blood cells, cellular waste products) from the peripheries (muscles, organs) back into the central circulatory system. If the vessels aren't working properly, this lymph fluid backs up in the soft tissues and looks like swelling. Lymphoedema most frequently affects the arms and legs, but can also be present in the groin, trunk, neck, and face.